Infertility in men can be a painful journey, especially when diagnosed with azoospermia (no sperm in semen) or nil sperm count. But modern medical science offers hope through advanced procedures like MESA (Microsurgical Epididymal Sperm Aspiration). This treatment has become a ray of hope for men worldwide who dream of becoming fathers.
In this article, we will break down what MESA is, how it works, its benefits, and why it’s considered one of the most effective treatments for male infertility.
What is MESA for Male Infertility Treatment?
MESA stands for Microsurgical Epididymal Sperm Aspiration. It is a specialized surgical technique used to retrieve healthy sperm directly from the epididymis (a tiny tube that stores sperm).
- Who needs MESA?
Men with obstructive azoospermia, vasectomy, or congenital absence of the vas deferens. - How does it work?
A microscope is used to carefully extract sperm from the epididymis. These sperms are then used in IVF (In Vitro Fertilization) or ICSI (Intracytoplasmic Sperm Injection) for achieving pregnancy.
👉 Simple definition: MESA is a safe and effective method to find and use healthy sperm when none are present in semen.
Why Choose MESA Over Other Azoospermia Treatments?
Compared to other sperm retrieval techniques, MESA offers higher success rates. Let’s see why:
- Better sperm quality than TESA (Testicular Sperm Aspiration).
- Higher chances of fertilization with ICSI.
- Less invasive and safer than repeated testicular biopsies.
- Useful for nil sperm count treatment in obstructive cases.
Conditions Treated by MESA
MESA is not a one-size-fits-all treatment. It is recommended in specific cases:
- Azoospermia treatment: Especially obstructive azoospermia, where sperm is made but not released.
- Nil sperm count treatment: For men who produce sperm, but it doesn’t appear in semen.
- Post-vasectomy cases: Men who wish to have children after vasectomy.
- Congenital conditions, Such as the absence of vas deferens.
Step-by-Step Process of MESA
Here’s what usually happens during a MESA procedure:
- Preparation: The patient is given anesthesia.
- Microsurgery: A high-powered microscope is used to locate the epididymis.
- Aspiration: Healthy, motile sperm are collected directly.
- Storage/Use: Sperms are either frozen for future use or immediately used in IVF/ICSI.
Duration: Around 1–2 hours.
Recovery time: Usually quick, with minimal discomfort.
Benefits of MESA for Male Infertility
✅ High-quality sperm retrieval
✅ Higher pregnancy success rates
✅ Minimally invasive procedure
✅ Safe for repeated use
✅ Ideal for azoospermia and nil sperm count treatment
Risks and Considerations
Like any surgical procedure, MESA also comes with some risks:
- Mild swelling or discomfort
- Bleeding or infection (rare)
- Need for IVF/ICSI (cannot achieve natural pregnancy directly)
Success Rates of MESA
Studies show that MESA provides better sperm retrieval rates compared to TESA or PESA. When combined with IVF/ICSI, the chances of pregnancy are significantly higher.
👉 For couples struggling with nil sperm count, MESA has become one of the most trusted treatment options worldwide.
Cost of MESA in India
The MESA procedure cost in India can range between ₹80,000 – ₹1,50,000, depending on the hospital, doctor’s expertise, and location. IVF/ICSI costs are usually separate but often offered as part of fertility packages.
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FAQs About MESA for Male Infertility
MESA (Microsurgical Epididymal Sperm Aspiration) is a surgical method to retrieve healthy sperm directly from the epididymis for IVF or ICSI.
Yes. MESA provides better quality sperm, especially for obstructive azoospermia, making it more effective than TESA.
MESA is not a cure but a solution. It helps retrieve sperm in cases of obstructive nil sperm count so couples can conceive via IVF/ICSI.
The procedure is done under anesthesia, so patients don’t feel pain during surgery. Post-surgery, mild discomfort may occur but heals quickly.
Success rates vary, but many centers report 60–80% fertilization rates when MESA is combined with ICSI
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For men diagnosed with azoospermia or nil sperm count, MESA for male infertility treatment offers a safe, effective, and hopeful solution. With advanced microsurgical techniques, doctors can retrieve healthy sperm and give couples a real chance at parenthood.
If you or your partner are struggling with infertility, consult a fertility specialist today and explore whether MESA is the right choice for you.
